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Common Topamax side effects may include: numbness or tingling in your arms and legs; flushing (warmth, redness, or tingly feeling); headache, dizziness, drowsiness, tired feeling; mood problems, confusion, feeling nervous, problems with thinking or memory; slow reactions, problems with speech or vision; nausea, diarrhea, stomach pain, loss of appetite, indigestion, weight loss; cold symptoms such as stuffy nose, sneezing, sore throat; or changes in your sense of taste.
Topiramate is quickly absorbed after oral use. Most of the drug (70%) is excreted in the urine unchanged. The remainder is extensively metabolized by hydroxylation, hydrolysis, and glucuronidation. Six metabolites have been identified in humans, none of which constitutes more than 5% of an administered dose. Take topiramate exactly as your doctor tells you to. It is usual to start topiramate treatment on a low dose (25 mg at night), and then for the dose to be increased gradually. A usual maintenance dose is 50-100 mg daily, taken either as a single dose or divided into two doses over the day.
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